Role of Polygenic Risk Score for Coronary Artery Disease and its Traditional Risk Factors with Progression of Coronary Artery Calcification
Das GesundheitswesenGemeinsame Jahrestagung – der Deutschen Gesellschaft für Epidemiologie e.V. (DGEpi), – der Deutschen Gesellschaft für Medizinische Soziologie e.V. (DGMS) und – der Deutschen Gesellschaft für Sozialmedizin und Prävention e.V. (DGSMP)(2017)
Abstract
Atherosclerosis is the primary cause of coronary artery disease (CAD). Several studies have examined the association of traditional CAD risk factors (CRF) for the progression of coronary artery calcification (CAC). Our study describes the genetic architecture of progression of CAC by assessing the combined effect of the risk alleles associated with CAD and its traditional risk factors.
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Key words
Polygenic Risk Scores
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