γ radiation-induced damage of nucleic acid bases, calf thymus DNA and DNA within MCF-7 breast cancer cells by [Cu₂(OAc)₄(tnz)₂]: a potential radiosensitizer

Ramesh Chandra Santra,Durba Ganguly,Debalina Bhattacharya,Parimal Karmakar,Abhijit Saha,Saurabh Das

New Journal of Chemistry（2017）

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摘要

A Cu(ii) complex of tinidazole is more radiosensitizing than it in radiation-induced damage of nucleic acids, calf thymus DNA and DNA in MCF-7 breast cancer cells. NO2˙− was modulated to strike a balance between efficacy and toxic side effects.

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γ radiation-induced damage of nucleic acid bases, calf thymus DNA and DNA within MCF-7 breast cancer cells by [Cu2(OAc)4(tnz)2]: a potential radiosensitizer

γ radiation-induced damage of nucleic acid bases, calf thymus DNA and DNA within MCF-7 breast cancer cells by [Cu₂(OAc)₄(tnz)₂]: a potential radiosensitizer