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High Testosterone Levels in Prostate Tissue Obtained By Needle Biopsy Correlate with Poor Prognosis Factors in Prostate Cancer Patients

Y. Miyoshi,S. Umemoto,H. Uemura,Y. Shibata,K. Sakamaki,S. Honma,K. Suzuki,Y. Kubota

Annals of Oncology（2014）

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Abstract
Aim: There has been no consensus on the prostatic tissue androgen concentrations in men with different stages and pathological grades of prostate cancer. In this study, testosterone (T) and dihydrotestosterone (DHT) concentrations in needle biopsy specimens of prostate were examined by newly developed ultra sensitive LC-MS/MS method.
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Key words
prostate cancer,prostate tissue,needle biopsy correlate,testosterone
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