Clinical profile of children presented with seizure in tertiary care hospital PMCH Patna, a retrospective study

Objective: To find the common causes of seizure and to classify seizure types in various age groups as well to predict outcome in relation to different variables. Design: Retrospective hospital-based, analytic and descriptive study. Setting: The Department of Paediatrics, PMCH, Patna. Participants/patients: This study includes all children in the age group 6 months to 15 years presented in the department of paediatrics with seizure. Outcome Measure(s): Demographic analysis and analysis of different seizure types, analysis of patient based on the cause of seizure as well as outcome of patient presented with seizure in relation to demographic, fever diagnosis and status epilepticus. Results: The total number of patient presented with seizure are 956 of them 574 were males and 382 were females. 562 had fever on presentation and most of them were less than 5 years of age amount to 562. The most common clinical seizure type were generalized tonic- clonic (60.5%). Seizure disorder (14.4%), febrile seizures (16.1%), central nervous system infections and neurocysticercosis were common etiologies. Tubercular meningitis was more common etiology in 6–10 years age group. Neurocysticercosis were more common in 11-15 years age group. Encephalitis were more common in children below 5 years of age. Conclusions: seizures are one of the common cause of hospitalization and high mortality. It can be inferred from this study that CNS infection are the most common cause of acute symptomatic seizure. Thus improvement in health care facilities like sanitation and immunization is warranted to prevent it. Keywords: Generalized tonic-clonic seizures, Neurocysticercosis, Encephalitis, Tubercular meningitis