Novel l-prolyl-l-leucylglycinamide (PLG) tripeptidomimetics based on a 2-azanorbornane scaffold as positive allosteric modulators of the D₂R

Ivo E. Sampaio-Dias,Carlos A. D. Sousa,Xerardo García-Mera,Joana Ferreira da Costa,Olga Caamaño,José E. Rodríguez-Borges

Organic & Biomolecular Chemistry（2016）

引用 11|浏览3

暂无评分

摘要

Replacement of l-prolyl residue in the PLG sequence by an enantiopure (1R,3S,4S)-2-azanorbornane scaffold afforded active peptidomimetics compatible with suppression of the C-terminal carboxamide pharmacophore.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要

Novel l-prolyl-l-leucylglycinamide (PLG) tripeptidomimetics based on a 2-azanorbornane scaffold as positive allosteric modulators of the D2R

Novel l-prolyl-l-leucylglycinamide (PLG) tripeptidomimetics based on a 2-azanorbornane scaffold as positive allosteric modulators of the D₂R