Polymorphism of chronic glomerulonephritis association with adprt1 gene val762ala

E. S. Kamyshova,M. Yu. Shvetsov,A. E. Shestakov,I. M. Kutyrina,V. V. Nosikov

Almanac of Clinical Medicine（2016）

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摘要

Association of polymorphic ADPRT1 gene Val762Ala marker, encoding poly(ADP-ribose)polymerase-l, with the development, course and progress of chronic glomerulonephritis was revealed during investigation. The risk of the chronic glomerulonephritis development is higher in patients-carriers of Val-allele and Val/Val-genotype and lower in those with Ala-allele and Ala/Ala-genotype.

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关键词

хронический гломерулонефрит,chronic glomerulonephritis,ген adprt1,adprt1,полиморфный маркер val762ala,val762ala polymorphism,генетическая предрасположенность,genetic susceptibility

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