Clinical Study of Simple Plasma Exchange in the Treatment of Severe Autoimmune Hepatitis

Objectives: Plasma Exchange (PE) in the treatment of severe autoimmune hepatitis and the clinical outcome of the clinical data were retrospectively analyzed. The clinical efficacy and safety of single plasma exchange (PE) in the treatment of autoimmune hepatitis were also evaluated. Method: The PE group of 22 patients was given conventional treatment of combined treatment of patients with simple PE while 21 cases of the control group were treated with comprehensive treatment. The efficacy of PE group and control group were compared within 2 weeks. Results: The clinical symptoms of 22 patients in PE group were significantly improved (p < 0.05); in total bilirubin (TBIL), (AST), (INR), (ALT) where the PE group (17/22) 77.27%, and control group (10/21) 47.62%. The difference was statistically significant (p < 0.05). Conclusion: Pure plasma exchange (PE) is an effective method for the treatment of severe autoimmune hepatitis (AIH).