Direct sprayed endothelialization, basement membrane and cell junction development on biological and artificial products are highly substrate-dependent and require optimized biofunctionalization
BioNanoMaterials(2015)
Abstract
AbstractOptimizing endothelialization of medical implants requires deep mechanistic insight into cellular adhesion, cell junction and physiological basement membrane development at the endothelial cell-to-scaffold substrate interface.We employed and standardized endothelial cells and fibrin hydrogel for simultaneous cell-plus-fibrin (EC-Fib) spray application using the MaslankaDirect sprayed endothelialization outlined the necessity for preconditioning acellular SynerGraft
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Key words
endothelialization,biofunctionalization,cell junction development,basement membrane,artificial products,substrate-dependent
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