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Tumor infiltrating IL-33 producing effector-memory CD8+ T cells in resected hepatocellular carcinoma prolong patient survival

SM Brunner,C Rubner,R Kesselring,M Martin,P Ruemmele,T Stempfl,A Teufel,HJ Schlitt,S Fichtner-Feigl

Zeitschrift für Gastroenterologie（2015）

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Abstract
Background: IL-33, a cytokine with pleiotropic functions, is elevated in serum of patients with hepatocellular carcinoma (HCC). This study investigated effects of local IL-33 expression in resected HCC on patient survival and on immunological and molecular tumor microenvironment.
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IL-33,Tumor Microenvironment
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