Platelet Volume Indices in Peripheral Artery Disease

This study aimed to assess the relationship between platelet volume indices (PVI) and peripheral artery disease (PAD). Platelet count (PLT), platelet distribution width (PDW), platelet large cell ratio (P-LCR), and mean platelet volume (MPV) were studied in adult patients with PAD. Two hundred ninety two patients were divided into two groups according to Fontaine classification. Group-1 contained 183 patients with stage I and II with mild symptoms, and the remaining 109 patients referred to the group-2 with severe symptoms. Blood samples were analyzed in a Sysmex SF3000 for platelet indices. There were no significant differences between patients in group-1 and group-2 in terms of PVI (P > 0.05). No significant correlation was identified between severity of peripheral vascular disease and PVI in patients with PAD. PVI seem not to associate with severity of PAD.