Noninflammatory musculoskeletal pain

Abstract Noninflammatory musculoskeletal pain is common in children and adolescents, and when persistent or widespread, can have a negative impact on physical and psychological well-being. Diagnostic labels and criteria are not uniform in the current literature, but musculoskeletal pain may present as widespread pain or juvenile fibromyalgia, complex regional pain syndrome, or in association with joint hypermobility. Chronic musculoskeletal pain, irrespective of its trigger, can bring persistent and recurrent distress, disability, and widespread family disruption. Once serious medical causes have been excluded by history, examination, and relevant investigations, the focus should be on rehabilitation. Multidisciplinary team management to facilitate cohesive working and the introduction of psychological and physical therapies can improve outcome. Further research is required to define the role of pharmacological interventions.