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Inhibition of Papain-Induced Emphysema in the Hamster by Human Alpha1-antitrypsin

Canadian Journal of Physiology and Pharmacology(1974)

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Abstract
Human alpha1-antitrypsin administered intratracheally in the hamster prevented the development of emphysematous changes induced by papain aerosol exposure. Inhibition appeared dose-related and detectable by both physiologic and histologic methods.
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Key words
emphysema,hamster,papain-induced
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