Differential Potencies of Naturally Occurring Regioisomers of Nitrolinoleic Acid in PPARγ Activation

Richard L. Alexander,Marcus W. Wright,Michael J. Gorczynski,Pamela K. Smitherman,Taro E. Akiyama,Harold B. Wood,Joel P. Berger,S. Bruce King,Charles S. Morrow

Biochemistry（2008）

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摘要

Previous studies demonstrated that the naturally occurring electrophile and PPARγ ligand, nitrolinoleic acid (NO2-LA), exists as a mixture of four regioisomers [Alexander, R. L., et al. (2006) Bioc...

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nitrolinoleic acid,regioisomers

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