Saturated heterocycles.176Synthesis and steric structure of quaternary azeto[2,1-a]isoquinoline stereoisomers

Starting from 1-substituted azeto[2,1-a]isoquinoline diastereomers, a number of quaternary salts were prepared. The reactions leading to the quaternary salts were stereospecific, independently of the configuration at C-1, resulting in diastereomers. The steric structures of the new compounds were proved by nmr spectroscopy.