Antibacterial Activity of Quinolone—Macrocycle Conjugates.

Elizabeth A. Jefferson,Eric E. Swayze,Stephen A. Osgood,Alycia Miyaji,Lisa M. Risen,Lawrence B. Blyn

ChemInform（2003）

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摘要

(vi) 0.12 M 2-fluoro-5-nitrobenzoic acid, 0.12 M HATU, 0.25 M collidine, DMF/DCM (1/1; v/v), 24 h; (vii) 0.2 M TREAT-HF, THF, 24 h; (viii) 0.2 M DBU, DMF; (ix) 1.5 M SnCl2, DMF/EtOH (10:1); (x) 0.12 M carboxylic acid (R 4 CO2H), 0.12 M HATU, 0.25 M collidine,

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antibacterial activity,quinolone—macrocycle conjugates

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