Investigation of genes and pathways involved in breast cancer subtypes through gene expression meta-analysis
Gene(2022)
Abstract
•-Gene expression meta-analysis of microarray data revealed subtype-specific genes for breast cancer.•-TMC5 was the only genes in Normal-like group.•-Meta-analysis’ data were validated by an independent comprehensive breast cancer dataset derived from the RNA-sequencing approach.•-There was 77.8% overlap in basal-specific genes between two extensive studies, meta-analysis and RNA-seq, and complete concordance in specific genes linked to other subtypes.
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Key words
Breast cancer,Breast cancer subtypes,Microarray,Gene expression meta-analysis
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