Differential Expression of Presynaptic Munc13-1 and Munc13-2 in Mouse Hippocampus Following Ethanol Drinking

Anamitra Ghosh,Sangu Muthuraju, Sean Badal,Jessica Wooden,J. Leigh Leasure,Gregg Roman,Joydip Das

Neuroscience（2022）

引用 1|浏览18

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摘要

•Ethanol upregulates Munc13-1, but downregulates Munc13-2 in the CA1.•Ethanol increased both Munc13-1 and Munc13-2 in the primary neuronal culture.•Ethanol upregulates GluN1 and GluN2A in the CA1 and in the primary culture.•Ethanol augments glutamatergic neurotransmission via Munc13 proteins.

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关键词

alcohol addiction,ethanol,presynaptic,Munc13,hippocampus,neurotransmitter,glutamate receptors

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