Employing Visible-Light Photoredox Catalysis in Multicomponent- Multicatalyst Reactions: One-Pot Synthesis of Spiroquinazolin-2-(thi)ones
JOURNAL OF ORGANIC CHEMISTRY(2022)
Abstract
The multicomponent-multicatalyst reaction ((MC)R-2) and visible-light catalysis have emerged as green and powerful strategies for achieving ideal syntheses. Here, we report the first example of a visible-light-induced approach toward spiroquinazolin(thi)ones. This (MC)R-2 features an eco-friendly energy source and solvent, metal-free catalysts, step- and atom- economy, a relay catalysis strategy, air as green oxidant, mild conditions, and easily accessible starting materials.
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Key words
multicomponent–multicatalyst reactions,synthesis,visible-light,one-pot
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