Endovascular Treatment of Large Vessel Occlusion Strokes Due to Intracranial Atherosclerotic Disease
JOURNAL OF STROKE(2022)
Abstract
Mechanical thrombectomy (MT) has become the gold-standard for patients with acute large vessel occlusion strokes (LVOS). MT is highly effective in the treatment of embolic occlusions; however, underlying intracranial atherosclerotic disease (ICAD) represents a therapeutic challenge, often requiring pharmacological and/or mechanical rescue treatment. Glycoprotein IIb/IIIa inhibitors have been suggested as the best initial approach, if reperfusion can be achieved after thrombectomy, with angioplasty and/or stenting being reserved for the more refractory cases. In this review, we focus on the therapeutic considerations surrounding the endovascular treatment of ICAD-related acute LVOS.
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Key words
Cerebral infarction,Intracranial embolism and thrombosis,Intracranial arteriosclerosis,Endovascular procedures,Angioplasty,Stents
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