Brainwave viscosity in propofol anaesthesia.

M S Fabus,M W Woolrich, C E Warnaby

British journal of anaesthesia(2022)

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摘要
Human EEG during propofol anaesthesia shows large-scale changes including traveling slow waves. Slow-wave saturation is a potentially individualised marker of loss of perception. However, much remains unclear about the dynamics of slow waves. Iterated empirical mode decomposition (itEMD) is a novel data-driven method for segregating data into physiologically relevant oscillatory modes. We used itEMD to identify spectral modes and their sources / sinks in propofol EEG. Viscosity is a physical quantity expressing the magnitude of resistance to flow. Considering traveling electric potentials in the brain as a flow, we extended the notion of viscosity to traveling brainwaves. Using this, we explored how brainwave viscosity changes in volunteer propofol anaesthesia.
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