Evidence that the gut microbiota regulates progression of neurodegeneration in a mouse model of tauopathy, in a sex- and ApoE isoform-dependent manner.
Alzheimer's & dementia : the journal of the Alzheimer's Association（2021）
摘要
Our results indicate that tau-mediated neurodegeneration occurs in a ApoE- dependent manner and is influenced by the gut microbiota and gender.
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