Peripheral inflammation and AD-related hippocampal neurodegeneration in prodromal AD patients.

Claire Chevalier,Moira Marizzoni,Giulia Quattrini,Nicola Lopizzo, Diego Albani,Jorge Jovicich,Annamaria Cattaneo,Giovanni B Frisoni

Alzheimer's & dementia : the journal of the Alzheimer's Association（2021）

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摘要

Higher expression of anti-inflammatory factors are associated to a lower hippocampal neurodegeneration and better clinical and pathophysiological outcome in prodromal AD patients. These preliminary results suggest that non-invasive peripheral inflammatory biomarkers could represent possible biomarkers to support the early diagnosis of AD.

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