Symptomatic presentation and cognitive performance in autopsy-confirmed, limbic-predominant, age-related TDP-43 encephalopathy with comorbid Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association(2021)
摘要
In this sample, LATE-NC was a very common comorbidity with ADNC, affecting over 1/3 of subjects. The co-occurrence of LATE-NC with ADNC may be distinguishable from ADNC alone through changes in behavior and cognitive performance. Although the specific features changed across the ADNC spectrum, the presence of LATE-NC was highly impactful clinically at all stages of ADNC severity.
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关键词
comorbid alzheimer,cognitive performance,autopsy-confirmed,limbic-predominant,age-related
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