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Exome Sequencing Identifies Rare Damaging Variants in ATP8B4 and ABCA1 As Risk Factors for Alzheimer’s Disease

Henne Holstege,Marc Hulsman,Camille Charbonnier,Benjamin Grenier-Boley,Olivier Quenez,Detelina Grozeva,Jeroen G. J. van Rooij,Rebecca Sims,Shahzad Ahmad,Najaf Amin,Penny J. Norsworthy,Oriol Dols-Icardo,Holger Hummerich,Amit Kawalia,Philippe Amouyel,Gary W. Beecham,Claudine Berr,Joshua C. Bis,Anne Boland,Paola Bossù,Femke Bouwman,Jose Bras,Dominique Campion,J. Nicholas Cochran,Antonio Daniele,Jean-François Dartigues,Stéphanie Debette,Jean-François Deleuze,Nicola Denning,Anita L. DeStefano,Lindsay A. Farrer,Maria Victoria Fernández,Nick C. Fox,Daniela Galimberti,Emmanuelle Genin, Johan J. P. Gille,Yann Le Guen,Rita Guerreiro,Jonathan L. Haines,Clive Holmes,M. Arfan Ikram,M. Kamran Ikram,Iris E. Jansen,Robert Kraaij, Marc Lathrop,Afina W. Lemstra,Alberto Lleó,Lauren Luckcuck,Marcel M. A. M. Mannens,Rachel Marshall,Eden R. Martin,Carlo Masullo,Richard Mayeux,Patrizia Mecocci,Alun Meggy,Merel O. Mol,Kevin Morgan,Richard M. Myers,Benedetta Nacmias,Adam C. Naj,Valerio Napolioni,Florence Pasquier,Pau Pastor,Margaret A. Pericak-Vance,Rachel Raybould,Richard Redon,Marcel J. T. Reinders,Anne-Claire Richard,Steffi G. Riedel-Heller,Fernando Rivadeneira,Stéphane Rousseau,Natalie S. Ryan,Salha Saad,Pascual Sanchez-Juan,Gerard D. Schellenberg,Philip Scheltens,Jonathan M. Schott,Davide Seripa,Sudha Seshadri,Daoud Sie,Erik A. Sistermans,Sandro Sorbi,Resie van Spaendonk,Gianfranco Spalletta,Niccolo’ Tesi,Betty Tijms,André G. Uitterlinden,Sven J. van der Lee,Pieter Jelle Visser,Michael Wagner,David Wallon,Li-San Wang,Aline Zarea,Jordi Clarimon,John C. van Swieten,Michael D. Greicius,Jennifer S. Yokoyama,Carlos Cruchaga,John Hardy,Alfredo Ramirez,Simon Mead,Wiesje M. van der Flier,Cornelia M. van Duijn,Julie Williams,Gaël Nicolas,Céline Bellenguez,Jean-Charles Lambert

Nature Genetics（2022）

Cited 74|Views28
Key words
Alzheimer's disease,Genetics research,Biomedicine,general,Human Genetics,Cancer Research,Agriculture,Gene Function,Animal Genetics and Genomics
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