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Structure-guided Stabilization of Pathogen-Derived Peptide-Hla-e Complexes Using Non-Natural Amino Acids Conserves Native TCR Recognition

Claire Barber,Victoria Arena De Souza,Rachel L. Paterson,Magdalena Martin-Urdiroz, Nitha Charles Mulakkal,Velupillai Srikannathasan,Mary Connolly, Gwilym Phillips, Tein Foong-Leong,Robert Pengelly,Vijaykumar Karuppiah,Tressan Grant,Marcin Dembek,Anil Verma, Dawn Gibbs-Howe,Thomas H. Blicher,Andrew Knox,Ross A. Robinson,David K. Cole,Sarah Leonard

European Journal of Immunology（2022）

Cited 11|Views23
Key words
HLA-E,TCR,non-natural amino acids,crystal structure,HIV
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