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Whole genome sequencing analysis of cognitively Wellderly individuals identifies potential protective genetic variants for Alzheimer's disease.

Gina M Peloso, Morgan A Rosser,Josh C Bis,Myriam Fornage,Eric Boerwinkle,Claudia L Satizabal,Bruce M Psaty,Oscar L Lopez,Thomas H Mosley,Yanbing Wang,Josée Dupuis,Anita L Destefano,Sudha Seshadri

Alzheimer's & dementia : the journal of the Alzheimer's Association（2021）

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Abstract
Although only variants in the APOE locus reached a genome-wide significance threshold, we found suggestive associations for Wellderly status with biological plausibility.
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Key words
alzheimer,potential protective genetic variants,whole genome,wellderly individuals
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