Locus coeruleus integrity predicts tau accumulation and memory dysfunction in autosomal dominant Alzheimer's disease.

Heidi I L Jacobs,Alex Becker,Kenneth Kwong,Diana Munera,Liliana A Ramirez-Gomez,Justin S Sanchez,Emma G Thibault,Clara Vila-Castelar,Ana Y Baena,Reisa A Sperling,Keith A Johnson,Francisco Lopera,Yakeel T Quiroz

Alzheimer's & dementia : the journal of the Alzheimer's Association（2021）

引用 1|浏览7

暂无评分

摘要

LC integrity is associated with the initial pathologic and clinical phenotypes of autosomal dominant Alzheimer's disease. These relationships are observed earlier in life than in sporadic AD, suggesting that LC integrity is not merely age-related but can be an early indicator of disease progression.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要