Dosimetric Modeling of Lymphopenia in Patients With Metastatic Cancer Receiving Palliative Radiation and PD-1 Immune Checkpoint Inhibitors

Jack M Qian,Elliot Akama-Garren,Jungwook Shin,Lauren Gunasti,Andrew Bang,Luke R G Pike,Clemens Grassberger,Jonathan D Schoenfeld

Advances in Radiation Oncology（2022）

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摘要

The RT dose to the whole body, bone, and LBVs and the modeled dose to circulating lymphocytes were correlated with lymphopenia in patients treated with palliative RT and anti-PD-1 immune checkpoint inhibitors. These findings may inform future radiation planning in this setting.

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