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Human Umbilical Cord Mesenchymal Stem Cells Promote Macrophage PD-L1 Expression and Attenuate Acute Lung Injury in Mice.

Chengshu Tu,Zhangfan Wang,E Xiang,Quan Zhang,Yaqi Zhang,Ping Wu,Changyong Li,Dongcheng Wu

Current stem cell research & therapy（2022）

Cited 7|Views17
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Abstract
Our results suggest that UC-MSCs attenuate ALI via PGE2-dependent reprogramming of macrophages to promote their PD-L1 expression.
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Key words
Human umbilical cord mesenchymal stem cells,acute lung injury,cyclooxygenase-2,programmed cell death protein ligand 1,prostaglandin E2,pulmonary inflammation
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