HPA axis dysfunction during morphine withdrawal in offspring of female rats exposed to opioids preconception
Neuroscience Letters(2022)
摘要
•Maternal history of opioid exposure increases offspring bodyweight.•No changes in somatic withdrawal in males and females.•Alterations of stress-related peptides in the amygdala during withdrawal.•Increased corticosterone in females during withdrawal.
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关键词
Intergenerational,Opioid,Morphine,Withdrawal,Crh,Ucn3,Corticosterone
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