Preparation and characterization of innovative electrospun nanofibers loaded with pharmaceutically applicable ionic liquids

International Journal of Pharmaceutics(2022)

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摘要
•Nanofibers with loaded ionic liquid were successfully produced.•Rised IL content reduce viscosity and increase conductivity electrospinning solution.•PEO-IL nanofibers' average diameter decreased with the increased IL content.•Thicker nanofibers were obtained with a higher molecular weight polymer.•Abcence of hydrogen bonds between ILs and PEO in electrospun nanofibers.
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关键词
Ionic liquid,Nanofiber,Electrospinning,Poorly soluble drug,Drug delivery
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