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Lycium barbarum polysaccharide protects against osteonecrosis of femoral head via regulating Runx2 expression

Qiang Song,Hai-Ming Yong,Lv-Lin Yang,Yu-Qi Liang,Ze-Xin Liu,Dong-Sheng Niu,Zhi-Gang Bai

Injury（2022）

Cited 3|Views7
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Abstract
•LBP enhanced osteoblast differentiation of BMSCs under hypoxia condition.•LBP treatment enhanced Runx2 and ALP expression in BMSCs.•LBP protects against ONFH via regulating Runx2 expression, which could be utilized to treat patients suffering ONFH.
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Key words
Osteonecrosis of femoral head,Lycium barbarum polysaccharide,Bone mesenchymal-derived stem cells,Osteoblast differentiation,Runx2,BMSC
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