Mycotoxins in Serum and 24-h Urine of Vegans and Omnivores from the Risks and Benefits of a Vegan Diet (RBVD) Study

MOLECULAR NUTRITION & FOOD RESEARCH(2022)

引用 7|浏览14
暂无评分
摘要
Scope: Vegans might have a higher exposure to mycotoxins due to their heightened consumption of typical mycotoxin containing food sources. Yet, data on internal exposure among vegans in comparison to omnivores are currently lacking. Methods and Results: This cross-sectional study includes 36 vegans and 36 omnivores (50% females, 30-60 years). A set of 28 and 27 mycotoxins is analyzed in 24-h urine and serum samples, respectively, by validated multi-mycotoxin methods (HPLC-MS/MS). Ochratoxin A (OTA), 2'R-OTA, and enniatin B in serum as well as deoxynivalenol-glucuronide in 24-h urine are quantified in 57-100% of the samples. Serum OTA levels are twofold higher in vegans than in omnivores (median 0.24 ng mL(-1) vs 0.12 ng mL(-1); p < 0.0001). No further significant differences were observed. Serum OTA levels are associated with intake of "vegan products" (r = 0.50, p < 0.0001) and "pasta & rice" (r = 0.33, p = 0.006). Sensitivity analyses advise cautious interpretation. Furthermore, serum levels of 2'R-OTA are related to coffee consumption (r = 0.64, p < 0.0001). Conclusion: The results indicate a higher exposure of vegans to OTA, but not to other mycotoxins. However, larger studies with repeated measurements are required to better evaluate the exposure to mycotoxins from plant-based diets.
更多
查看译文
关键词
24-h urine, biomarker of exposure, blood, multi-mycotoxin method, vegan
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要