GNLY gene polymorphism: A potential role in understanding psoriasis pathogenesis.

In patients with psoriasis, the GNLY rs7908 CC genotype alongside with C allele played a preventative function and reduced disease severity (as shown by PASI score). Detection of GG genotype points out that a psoriatic case will run a progressive course, will have a severe pattern in the future, and will develop multiple site affection.