Bioactive polyacetylenes from Bidens pilosa L and their anti-inflammatory activity.

A new polyacetylenic glucoside together with three known compounds were isolated from the whole herb of L. The structure elucidation of these four compounds was employed by combining NMR and HR-MS data as 4---D-glucopyranosyloxy-1-hydroxy- 6-()-tetradecene-8,10,12-triyne (), 3---D-glucopyranosyloxy-1-hydroxy-6-()-tetradec- ene-8,10,12-triyne (), 2---D-glucopyranosyloxy-1-hydroxy-5-(-tetradecene-7,9,11-triy- ne () and icthyothereol acetate (). Additionally, bioactivity study showed that these compounds have potential anti-inflammatory activity. This study has certain guiding significance for the development and utilisation of polyacetylene compounds in L.