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Elucidation of molecular mechanism for colistin resistance among Gram-negative isolates from tertiary care hospitals

Maleeha Urooj,Rooh Ullah,Sakhawat Ali,Aisha Mohyuddin, Hira Mehboob Mirza,Rani Faryal

Journal of Infection and Chemotherapy（2022）

Cited 3|Views3
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Abstract
Antimicrobial resistance is a growing concern of global public health. The emergence of colistin-resistance among carbapenem-resistant (CPR) Gram-negative bacteria causing fear of pan-resistance, treatment failure, and high mortality across the globe.
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Key words
Colistin resistance,Gram-negatives,Carbapenem-resistance,Molecular determinants,mcr gene,Non-synonymous mutation
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