Comparison between HEMNMA-3D and Traditional Classification Techniques for Analyzing Biomolecular Continuous Shape Variability in Cryo Electron Subtomograms
2021 4th International Conference on Bio-Engineering for Smart Technologies (BioSMART)（2021）
摘要
Cryogenic electron tomography (cryo-ET) allows studying biological macromolecular complexes in cells by three-dimensional (3D) data analysis. The complexes continuously change their shapes (conformations) to achieve biological functions. The shape heterogeneity in cryo-ET is a bottleneck for comprehending biological mechanisms and developing drugs. Cryo-ET data suffer from a low signal-to-noise ra...
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关键词
Visualization,Three-dimensional displays,Shape,Dynamics,Tomography,Motion pictures,Biology
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