Design, Synthesis and Evaluation of Novel (E)-N'-((1-(4-chlorobenzyl)-1H-indol-3-yl)methylene)-2-(4-oxoquinazolin-3(4H)-yl)acetohydrazides as Antitumor Agents.
Anti-cancer agents in medicinal chemistry（2022）
摘要
Compound 5e has emerged as a potential hit for further design and development of caspases activators and anticancer agents.
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关键词
Acetohydrazides,caspase activation,cytotoxicity,docking simulation,quinazolin-4(3H)-one,synthesis
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