Biomarkers of nicotine exposure correlate with the Hooked on Nicotine Checklist among adolescents in California, United States

Addictive Behaviors(2022)

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摘要
•The Hooked on Nicotine Checklist (HONC) measures adolescents' nicotine dependence.•This study biochemically validates HONC among adolescent e-cigarette users.•Nicotine dependence symptoms were reported at low levels of nicotine exposure.•Greater HONC score was associated with higher salivary nicotine metabolite levels.
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关键词
HONC,LC-MS/MS
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