Comparison of SARS-CoV-2 antibody response after two doses of mRNA and inactivated vaccines in multiple sclerosis patients treated with disease-modifying therapies

Multiple Sclerosis and Related Disorders(2022)

Cited 17|Views1
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Abstract
•No difference between multiple sclerosis patients without treatment and healthy people in terms of COVID-19 vaccine response.•Multiple sclerosis patients on disease-modifying treatment have lower antibody responses than those without treatment.•mRNA vaccine resulted in a more significant antibody response than an inactivated vaccine in multiple sclerosis patients treated with disease-modifying therapies.•Fingolimod and ocrelizumab resulted in lower antibody response than other disease-modifying therapies in both vaccine types.•mRNA vaccine resulted in greater antibody response in all treatment groups except for ocrelizumab.
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Key words
Multiple sclerosis,COVID-19,mRNA vaccine,Disease-modifying therapy
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