A robust, cost-effective and widely applicable whole-genome sequencing protocol for capripoxviruses

•Robust method for the genomic characterization of all Capripoxviruses.•Pre-sequencing enrichment method based on targeted long-range PCR amplification.•Method applicable to low titre samples such as blood samples and vaccine batches.•Viral DNA enrichment compatible with various sample types and sequencing platforms.•Complete coding genome sequencing evaluated on three different sequencing platforms.