Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids.
Hepatology (Baltimore, Md.)（2022）
摘要
Highly proliferative human CCA cells rely on lipid and lipoprotein uptake to fuel FA catabolism, suggesting that inhibition of FAO and/or lipid uptake could represent a therapeutic strategy for this CCA subclass.
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关键词
cholangiocarcinoma,lipid metabolism,pathogenesis,precision medicine,proliferative subtype
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