Associations of pro-protein convertase subtilisin-like kexin type 9, soluble low-density lipoprotein receptor and coronary artery disease: A case-control study

Jie Peng, Cathleen Y Xing,Ketong Zhao, Jingti Deng,Daiana Alvarez Olmedo,Zhiyong Ma,Mingxiang Zhang,Ying Wang

International Journal of Cardiology（2022）

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摘要

•PCSK9 and sLDLR are risk factors for CAD•PCSK9 and sLDLR levels were significantly increased, and PCSK9 gradually increased with the increase of sLDLR•Higher PCSK9 level might be an indicator for coronary artery stenosis.•sLDLR was positively corrected with PCSK9, which confounded the association between CAD and PCSK9.

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关键词

Soluble low-density lipoprotein receptor,Pro-protein convertase subtilisin-like kexin type 9,Coronary artery disease

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