Perylenequinone derivatives from the endolichenic fungus Phialocephala fortinii .

Five undescribed perylenequinone derivatives (PQDs) phialocephalarins H - L (-), together with two known PQDs phialocephalarins A - B (, ) and one known spirobisnaphthalene palmarumycin P3 () were isolated from the endolichenic fungus Their structures were elucidated on the basis of NMR and HRESIMS data as well as electronic circular dichroism (ECD) calculations. Compounds , , , and - were evaluated for cytotoxic activities against NCI-H460, NCI-H446, PC3, and EC109 cell lines. The results showed that compounds , , , and showed cytotoxic activities against EC109 cells with IC values ranging from 24.5 to 33.3 M.