Copy number variation of GAL3ST1 gene is associated with growth traits of Chinese cattle.

Animal biotechnology(2022)

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Abstract
Copy number variation (CNV) is a type of genomic structural variation, and the research on it has flourished in recent years. According to the high-throughput sequencing data, we found that the copy number variation region of the gene was correlated with the growth traits of bovine. It is significant that we study the CNV of gene and process the association analysis between results of Q-PCR and growth traits of Chinese cattle. In this research, SPSS software was used to detect the distribution of gene copy number in four cattle breeds and the correlation of growth traits was analyzed. Correlation analysis showed that CNV had positive effects on some growth traits of bovine ( < 0.05). In addition, the study detects the expression of gene in different tissues of Xia'nan cattles on mRNA level. The result showed that gene has different expression conditions in different tissues, results showed that the expression level was high in intestine and low in liver tissue. In a word, we speculated that the gene can be used as a molecular marker and this study confirmed that the CNV of it can provide theoretical basis for molecular breeding of cattle in China.
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Key words
Chinese cattle,GAL3ST1 gene,association analysis,copy number variations (CNVs),growth traits
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