Detection and analysis of cerebral aneurysms based on X-ray rotational angiography - the CADA 2020 challenge

•The Cranial Aneurysm Detection and Analysis Challenge (CADA) provides a benchmarking dataset (3D rotational X-ray angiography) and evaluation framework for: (a) Aneurysm detection, (b) Aneurysm segmentation, (c) Rupture risk estimation.•The paper provides a comparison of image-based aneurysm rupture risk assessment approaches from different domains such as (a) Weighted parameter combinations (clinical score), (b) Radiomics-based machine learning.(c) Computation fluid dynamics.•The paper assesses the performance of a fully automatic pipeline for the detection and rupture risk assessment.