Distribution of kisspeptin system and its relation with gonadotropin-releasing hormone in the hypothalamus of the South American plains vizcacha, Lagostomus maximus

Alejandro Raúl Schmidt,Pablo Ignacio Felipe Inserra,Santiago Andrés Cortasa,Sofía Proietto,Victoria Fidel,Julia Halperin,Alfredo Daniel Vitullo,Verónica Berta Dorfman

General and Comparative Endocrinology（2022）

Cited 2|Views3

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Abstract

•AVPV of vizcacha showed sexual dimorphism with a significant smaller area in males.•AVPV depicted three subpopulations of neurons: double Dyn + NKB+, double Kiss + NKB+, and single NKB+.•Kiss and Dyn, and Kiss and GnRH, are always expressed in different cells.•KNDy cells were detected in ARC nucleus.•Kiss immunoreactive afferent contacts make close appositions onto somas and dendrites of GnRH + GPR54 + cells.

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Key words

Kisspeptin,Dynorphin A,Neurokinin B,GnRH,Hypothalamus,Vizcacha

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