Focus Ultrasound-Induced Blood-Brain Barrier opening enhances anti-pGlu3 Aβ mAb delivery and amyloid-beta plaque clearance.

Praveen Bathini,Tao Sun,Qiaoqiao Shi,Yongzhi Zhang,Nadine Taudte,Mathias Schenk,Thore Hettmann,Stephan Schilling,Nathan McDannold,Cynthia A Lemere

Alzheimer's & dementia : the journal of the Alzheimer's Association（2021）

引用 0|浏览1

暂无评分

摘要

Transient opening of the BBB by FUS increased 07/2a delivery to the brain, improved cognition, and enhanced Ab clearance in aged APP/PS1dE9 mice, suggesting that FUS increased efficacy of the 07/2a mAb.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要