Role of arachidonic acid lipoxygenase pathway in Asthma

•The AA LOXs metabolism pathways play a key role in immunological response and inflammation diseases, such as asthma.•LOXs and their main metabolites in asthma play both anti- and pro-inflammatory role in asthma airway inflammation.•Regulations of LOX expression and activity are associated with the pathogenesis of asthma.•The treatment targe AA LOXs metabolism pathways are application for clinical use.