MNX1-HNF1B Axis Is Indispensable for Intraductal Papillary Mucinous Neoplasm Lineages Hiroyuki Kato , Keisuke Tateishi , Hiroaki Fujiwara , Takuma Nakatsuka , Keisuke Yamamoto , Yotaro Kudo , Yoku Hayakawa , Hayato Nakagawa , Yasuo Tanaka , Hideaki Ijichi , Motoyuki Otsuka , Dosuke Iwadate , Hiroki Oyama , Sachiko Kanai , Kensaku Noguchi , Tatsunori Suzuki , Tatsuya Sato , Ryunosuke Hakuta , Kazunaga Ishigaki , Kei Saito , Tomotaka Saito , Naminatsu Takahara , Takahiro Kishikawa , Tsuyoshi Hamada , Ryota Takahashi , Koji Miyabayashi , Suguru Mizuno , Hirofumi Kogure , Yousuke Nakai , Yoshihiro Hirata , Atsushi Toyoda , Kazuki Ichikawa , Wei Qu , Shinichi Morishita , Junichi Arita , Mariko Tanaka , Tetsuo Ushiku , Kiyoshi Hasegawa , Mitsuhiro Fujishiro , Kazuhiko Koike Gastroenterology（2022）
摘要
Integrative molecular and biological assays were performed on human pancreatic cancer organoids. Chromatin conformation stratified the lineage differences in pancreatic cancers and reflected their biological features.
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关键词
Intraductal Papillary Mucinous Neoplasm, HNF1B, MNX1, Epigenetics, Chromatin Structure
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